sulfhemoglobin

Pathology: - oxidativie sulfation of 1 or 2 of the 4 heme groups of hemoglobin - occurs on exposure to certain toxic agents - iron remains in the ferrous state, but oxygen affinity is about 100 fold less than for hemoglobin A - sulfur is found bound to the porphyrin ring - sulfhemoglobin persists for the life of the red cell - results in cyanosis - symptoms are not usually present

Related

sulfhemoglobin in blood sulfhemoglobin/hemoglobin in blood

Properties

COMPARTMENT: cytoplasm CELL: erythrocyte SUBUNITS: hemoglobin alpha chain :QUANTITY 2 :MOTIF heme-binding site :COFACTOR_BOUND heme :QUALITIES sulfur :METAL FE+2 hemoglobin beta chain :QUANTITY 2 :MOTIF heme-binding site :COFACTOR_BOUND heme :QUALITIES sulfur :METAL FE+2