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sulfatide; galactocerebroside sulfate
Function:
- role in myelin function & stability
Expression:
- primarily in the oligodendrocytes in the central nervous system
Pathology:
- metachromatic leukodystrophy is a lysosomal storage disease characterized by accumulation of sulfatides due to an inability to degrade them in lysosomes
- alterations in sulfatide metabolism may occureearly in the course of Alzheimer's disease
Related
arylsulfatase-A (cerebroside sulfatase, [contains: arylsulfatase A component B; arylsulfatase A component C], ARSA)
General
galactocerebroside (galactosylceramide)
sulfate (SO4=)
Properties
COMPARTMENT: plasma membrane
References
- Wikipedia: Sufatide
http://en.wikipedia.org/wiki/Sulfatide