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suberosis; corkhandler disease; corkworker lung
Etiology:
- Penicillium glabrum from exposure to moldy cork dust
- Chrysonilia sitophilia, Aspergillus fumigatus, Mucor macedo & uncontaminated cork dust may also play a role
Pathology:
- lymphocytic alveolitis
Clinical manifestations:
- asthma-like syndrome
- extrinsic allergic alveolitis
- chronic bronchitis with bronchiectasis
Laboratory:
- lung biopsy
- cork dust within lesions
- scalene node biopsy
Special laboratory:
- pulmonary function testing
- restrictive lung disease
- bronchoalveolar lavage
Radiology:
- chest X-ray may be normal
- computed tomography of the thorax
- ground glass opacities
General
occupational lung disease
hypersensitivity pneumonitis; extrinsic allergic alveolitis; pigeon breeder's lung; bird fancier's lung; farmer's lung; allergic pneumonitis
References
- Wikipedia: Suberosis
http://en.wikipedia.org/wiki/Suberosis
- Pimentel JC and Avila R
Respiratory disease in cork workers (`suberosis')
Thorax. 1973 July; 28(4): 409-423
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC470051/
- Morais A et al
Suberosis and Bird Fancier's Disease: a comparative study of
radiologic, functional and bronchoalveolar lavage profiles.
J Invest Allergol Clin Immunol 2004 14(1):26
http://www.jiaci.org/issues/vol14issue01/26-33.pdf