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Study of Osteoporotic Fractures (SOF)

Study characteristics: - large, community-based observational study - compared never users of estrogen vs current users of estrogen Results: 1) estrogen protected against a) hip fracture (RR 0.60) b) wrist fracture (RR 0.39) c) all non-spinal fractures (RR 0.66) 2) only users of estrogen who began within 5 years of menopause were found to benefit

Related

estrogen hormone replacement therapy (HRT); estrogen replacement therapy; postmenopausal hormone replacement therapy osteoporosis

General

case-control study

References

  1. Greenwood G. In: Intensive Course in Geriatric Medicine & Board Review, Marina Del Ray, CA, Sept 12-15, 2001
  2. Cauley JA et al, Ann Intern Med 122:9, 1995