structural maintenance of chromosomes protein 5 (hSMC5, SMC5, KIAA0594, SMC5L1)

Function: - core component of the SMC5-SMC6 complex - forms a heterodimer with SMC6 Structure: - flexible hinge domain, which separates the large intramolecular coiled coil regions, allows the heterotypic interaction with the corresponding domain of SMC6, forming a V-shaped heterodimer (putative) - belongs to the SMC family, SMC5 subfamily Compartment: - nucleus - associates with chromatin Expression: widely expressed

Properties

SIZE: MW = 129 kD entity length = 1101 aa COMPARTMENT: cell nucleus MOTIF: ATP-binding site NAME: ATP-binding site SITE: 80-87 coiled coil {207-445} coiled coil {647-828} coiled coil {888-927}

Database Correlations

UniProt Q8IY18 Pfam PF02463

References

UniProt :accession Q8IY18