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steroid biosynthesis
Biochemistry:
- steroid biosynthesis 1
- enzyme: multienzyme-complex
- cholesterol desmolase, adrenodoxin, adrenodoxin reductase
- substrate: cholesterol + NADPH + O2
- product: pregnenolone + isocaproate + NADP
- steroid biosynthesis 2
- enzyme: multienzyme-complex
- steroid-17-hydroxylase, cytochrome-P450 reductase
- substrate: pregnenolone + O2 + NADPH
- product: 17-hydroxypregnenolone + NADP
- steroid biosynthesis 3
- enzyme: multienzyme-complex
- steroid-17-hydroxylase, cytochrome-P450 reductase
- substrate: 17-hydroxypregnenolone + O2 + NADPH
- product: ((dehydroepiandrosterone) (NADP)))
- steroid biosynthesis 4
- enzyme: 3-hydroxysteroid dehydrogenase
- substrate: pregnenolone + NADP
- product: progesterone + NADPH
- steroid biosynthesis 5
- enzyme: 3-hydroxysteroid dehydrogenase
- substrate: 17-hydroxypregnenolone + NADP
- product: 17-hydroxyprogesterone + NADPH
- steroid biosynthesis 6
- enzyme: 3-hydroxysteroid dehydrogenase
- substrate: dehydroepiandrosterone + NADP
- product: androstenedione + NADPH
- steroid biosynthesis 7
- enzyme: multienzyme-complex
- steroid-17-hydroxylase, cytochrome-P450 reductase
- substrate: ((progesterone) (O2) (NADPH))
- product: ((17-hydroxyprogesterone) (NADP)))
- steroid biosynthesis 8
- enzyme: ((multienzyme-complex
- steroid-17-hydroxylase, cytochrome-P450 reductase
- substrate: 17-hydroxyprogesterone + O2 + NADPH
- product: androstenedione + NADP
Related
steroid
Specific
adrenal steroid biosynthesis
gonadal steroid biosynthesis
General
biosynthetic pathway or anabolic pathway
Database Correlations
Kegg map/map00100