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StemRegenin 1 (SR1)
Indication:
- experimental agent for expanding populations of human hematopoietic stem cells
Mechanism of action:
- aryl hydrocarbon receptor antagonist
General
hematologic agent
receptor antagonist
References
- Boitano AE et al.
Aryl hydrocarbon receptor antagonists promote the expansion of
human hematopoietic stem cells.
Science 2010 Sep 10; 329:1345
PMID: 20688981
http://dx.doi.org/10.1126/science.1191536
- Sauvageau G and Humphries RK.
The blood stem cell Holy Grail?
Science 2010 Sep 10; 329:1291.
PMID: 20829472
http://dx.doi.org/10.1126/science.1195173