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SRGAP2 (SLIT-ROBO Rho GTPase activating protein 2) gene
3p25.3
Structure:
- a segmental duplication of chromosome 1 involving SRGAP2 is one of the few features distinguishing the human genome from the chimpanzee genome. [1]
Related
SLIT-ROBO Rho GTPase-activating protein 2; srGAP2; formin-binding protein 2; Rho GTPase-activating protein 34 (SRGAP2, ARHGAP34, FNBP2, KIAA0456, SRGAP2A)
General
evolutionary divergent human gene
Properties
TEMPLATE-FOR: messenger RNA
TEMPLATE-FOR: SLIT-ROBO Rho GTPase-activating protein 2
LOCUS: human chromosome-1 Q32
MOTIF: transcription factor binding site
transcriptional start site
exon
intron
transcriptional termination site
Database Correlations
OMIM 606524
LOCUS-LINK correlations
References
- Fortna A, Kim Y, MacLaren E, Marshall K, Hahn G, Meltesen L,
Brenton M, Hink R, Burgers S, Hernandez-Boussard T, Karimpour-
Fard A, Glueck D, McGavran L, Berry R, Pollack J, Sikela JM.
Lineage-specific gene duplication and loss in human and great
ape evolution.
PLoS Biol. 2004 Jul;2(7):E207. Epub 2004 Jul 13.
PMID: 15252450