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SRB subcomplex

A subcomplex that associates with RNA polymerase 2, TFIIH, & TFIIB to form the pol II holoenzyme in yeast.

General

fungus-specific molecule molecular complex nuclear protein

Properties

COMPARTMENT: cell nucleus SUBUNITS: SRB2 protein MOTIF: binding site FOR-BINDING-OF: TATA-box-binding protein SRB4 protein SRB5 protein MOTIF: binding site FOR-BINDING-OF: TATA-box-binding protein SRB6 protein SRB7 protein SRB8 protein SRB9 protein SRB10 protein STATE: active state MOTIF: S/T phosphorylation site kinase domain MOTIF: ATP-binding site NAME: ATP-binding site SRB11 protein MOTIF: ubiquitination site (destruction box, D-box) SITE: N-TERMINAL FOR-BINDING-OF: ubiquitin PEST region cyclin box FOR-BINDING-OF: cyclin-dependent kinase SUG1 protein GAL1/SPT13

References

Koleske et al TIBS 20:113 1995

Component-of

RNA polymerase-2 yeast holoenzyme

Components

GAL1/SPT13 SRB10 protein SRB11 protein SRB2 protein SRB4 protein SRB5 protein SRB6 protein SRB7 protein SRB8 protein SRB9 protein SUG1 protein