Search
SRB subcomplex
A subcomplex that associates with RNA polymerase 2, TFIIH, & TFIIB to form the pol II holoenzyme in yeast.
General
fungus-specific molecule
molecular complex
nuclear protein
Properties
COMPARTMENT: cell nucleus
SUBUNITS: SRB2 protein
MOTIF: binding site
FOR-BINDING-OF: TATA-box-binding protein
SRB4 protein
SRB5 protein
MOTIF: binding site
FOR-BINDING-OF: TATA-box-binding protein
SRB6 protein
SRB7 protein
SRB8 protein
SRB9 protein
SRB10 protein
STATE: active state
MOTIF: S/T phosphorylation site
kinase domain
MOTIF: ATP-binding site
NAME: ATP-binding site
SRB11 protein
MOTIF: ubiquitination site (destruction box, D-box)
SITE: N-TERMINAL
FOR-BINDING-OF: ubiquitin
PEST region
cyclin box
FOR-BINDING-OF: cyclin-dependent kinase
SUG1 protein
GAL1/SPT13
References
Koleske et al TIBS 20:113 1995
Component-of
RNA polymerase-2 yeast holoenzyme
Components
GAL1/SPT13
SRB10 protein
SRB11 protein
SRB2 protein
SRB4 protein
SRB5 protein
SRB6 protein
SRB7 protein
SRB8 protein
SRB9 protein
SUG1 protein