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spindle & kinetochore-associated protein 2 (protein FAM33A, FAM33A, SKA2)
Function:
- required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubulesleading to silencing of the spindle checkpoint
- role in maintenance of metaphase plate &/or spindle checkpoint silencing
- required for SKA1 localization
Structure: belongs to the SKA2 family
Compartment:
- spindle, kinetochore
- localizes to both mitotic spindle & kinetochore-associated proteins
General
cytoskeletal protein
Properties
SIZE: MW = 14 kD
entity length = 121 aa
COMPARTMENT: cytoplasm
Database Correlations
UniProt Q8WVK7
References
UniProt :accession Q8WVK7