sphingolipid delta(4)-desaturase DES1 (degenerative spermatocyte homolog 1, membrane lipid desaturase, migration-inducing gene 15 protein, DEGS1, DES1, MLD, MIG15)

Function: - has sphingolipid-delta-4-desaturase activity - converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine) Structure: - belongs to the fatty acid desaturase family, DEGS subfamily Compartment: endoplasmic reticulum membrane Expression: ubiquitous

General

membrane protein oxidoreductase

Properties

SIZE: entity length = 323 aa MW = 38 kD COMPARTMENT: endoplasmic reticulum MOTIF: transmembrane domain {41-61} transmembrane domain {68-88} transmembrane domain {102-122} transmembrane domain {152-172} transmembrane domain {184-204} transmembrane domain {209-229}

Database Correlations

UniProt O15121 PFAM correlations

References

UniProt :accession O15121