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Sperm equatorial segment protein 1 (SP-ESP, Equatorial segment protein, ESP, glycosylated 38 kD sperm protein C-7/8) (SPESP1)
Structure: belongs to the SPESP1 family
Compartment:
- acrosome
- small proacrosomal granules (during Golgi phase)
- enlarged acrosomal vesicles (during cap phase)
- acrosome (during the elongating phase)
- equatorial segment of acrosome (during maturation phase)
Expression:
- highly expressed in testis, where it is localized in the acrosome of postmeiotic stages of spermiogenesis (round & elongating spermatids & in ejaculated spermatozoa) (at protein level)
- poorly expressed in placenta & fetal lung
General
glycoprotein
testis-specific protein
Properties
SIZE: MW = 39 kD
entity length = 350 aa
COMPARTMENT: golgi
MOTIF: signal sequence {1-19}
N-glycosylation site {N128}
alanine-rich region {266-271}
MOTIF: alanine residue (SEVERAL)
Database Correlations
UniProt Q6UW49
References
UniProt :accession Q6UW49