SPARC-related modular calcium-binding protein 2 (secreted modular calcium-binding protein 2, SMOC-2, smooth muscle-associated protein 2, SMAP-2, SMOC2, SMAP2, MSTP117)

Compartment: secreted Alternative splicing: named isoforms=2

General

Ca+2 binding protein glycoprotein secreted protein

Properties

SIZE: MW = 50 kD entity length = 446 aa COMPARTMENT: extracellular compartment MOTIF: signal sequence {1-21} Kazal-type serine protease inhibitor domain {40-84} MOTIF: cysteine residue {X+0} MODIFICATION: cysteine residue {X+X4} cysteine residue {X+X1} MODIFICATION: cysteine residue {X+X3} cysteine residue {X+X2} MODIFICATION: cysteine residue {X+X5} cysteine residue {X+X3} MODIFICATION: cysteine residue {X+X1} cysteine residue {X+X4} MODIFICATION: cysteine residue {X+0} cysteine residue {X+X5} MODIFICATION: cysteine residue {X+X2} FOR-BINDING-OF: serine protease thyroglobulin type 1 {87-153} MOTIF: cysteine residue {C90} MODIFICATION: cysteine residue {C113} cysteine residue {C113} MODIFICATION: cysteine residue {C90} cysteine residue {C124} MODIFICATION: cysteine residue {C131} cysteine residue {C131} MODIFICATION: cysteine residue {C124} cysteine residue {C133} MODIFICATION: cysteine residue {C153} cysteine residue {C153} MODIFICATION: cysteine residue {C133} N-glycosylation site {N206} thyroglobulin type 1 {213-281} MOTIF: cysteine residue {C216} MODIFICATION: cysteine residue {C240} cysteine residue {C240} MODIFICATION: cysteine residue {C216} cysteine residue {C251} MODIFICATION: cysteine residue {C258} cysteine residue {C258} MODIFICATION: cysteine residue {C251} cysteine residue {C260} MODIFICATION: cysteine residue {C281} cysteine residue {C281} MODIFICATION: cysteine residue {C260} EF hand SITE: 347-382 MOTIF: N-glycosylation site {N362} EF hand SITE: 384-419

Database Correlations

OMIM 607223 UniProt Q9H3U7 PFAM correlations

References

UniProt :accession Q9H3U7