sry-box-8 protein; transcription factor sox-8 (sox8)

Function: - may play a role in central nervous system, limb & facial development - may be involved in male sex determination - binds the consensus motif 5'-[AT][AT]CAA[AT]G-3' (putative) Structure: contains 1 HMG box DNA-binding domain Compartment: nucleus (putative)

General

sex-determining region Y box protein; sry-box protein; sox protein (SOX) transcription factor (TF)

Properties

SIZE: entity length = 446 aa MW = 47 kD COMPARTMENT: cell nucleus MOTIF: HMG box SITE: 102-170

Database Correlations

UniProt P57073 Pfam PF00505 Entrez Gene 30812 Kegg hsa:3081

References

UniProt :accession P57073