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sry-box-4 protein; transcription factor SOX-4 (sox4)
Function:
- transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif
- interacts with UBE2I
Structure: contains 1 HMG box DNA-binding domain
Compartment: nucleus
Expression: testis, brain, & heart
General
phosphoprotein
sex-determining region Y box protein; sry-box protein; sox protein (SOX)
transcription factor (TF)
Properties
SIZE: entity length = 474 aa
MW = 47 kD
COMPARTMENT: cell nucleus
MOTIF: HMG box
SITE: 59-127
Ser phosphorylation site {S276}
serine-rich region {386-397}
MOTIF: serine residue (SEVERAL)
Database Correlations
OMIM 184430
UniProt Q06945
Pfam PF00505
Entrez Gene 6659
Kegg hsa:6659
References
UniProt :accession Q06945