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solute carrier organic anion transporter family member 6A1 (solute carrier family 21 member 19, organic anion-transporting polypeptide I, OATP-I, organic anion-transporting polypeptide 6A1, gonad-specific transporter, GST, cancer/testis antigen 48, CT48, SLCO6A1g OATP6A1g SLC21A19)
Structure:
- belongs to the organo anion transporter (TC 2.A.60) family
Compartment: membrane (putative)
Alternative splicing: named isoforms=3
Expression:
- srongly expressed in testis
- weakly expressed in spleen, brain, fetal brain & placenta
- detected in lung tumors
General
glycoprotein
membrane protein
organic anion transporting polypeptide (OATP)
solute carrier family 21 (SLC21, SLC21A)
Properties
SIZE: entity length = 719 aa
MW = 79 kD
COMPARTMENT: cellular membrane
MOTIF: cysteine-rich region {89-118}
transmembrane domain {108-128}
transmembrane domain {145-165}
transmembrane domain {171-191}
transmembrane domain {231-251}
transmembrane domain {264-284}
N-glycosylation site {N300}
transmembrane domain {310-330}
transmembrane domain {424-444}
transmembrane domain {455-475}
N-glycosylation site {N497}
N-glycosylation site {N546}
transmembrane domain {580-600}
transmembrane domain {615-635}
N-glycosylation site {N661}
transmembrane domain {670-690}
Database Correlations
UniProt Q86UG4
PFAM correlations
References
UniProt :accession Q86UG4