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solute carrier family 38 member 3; Na+ coupled neutral amino acid transporter 3; system N amino acid transporter 1; N-system amino acid transporter 1 (SLC38A3, G17, NAT1, SN1, SNAT3)

Function: - Na+ dependent amino acid/proton antiporter - mediates electrogenic cotransport of glutamine & Na+ in exchange for H+ - also recognizes histidine, asparagine & alanine - may mediate amino acid transport in either direction under physiological conditions - may play role in nitrogen metabolism & synaptic transmission Structure: - belongs to the amino acid/polyamine transporter 2 family Compartment: cell membrane

General

glycoprotein phosphoprotein solute carrier family 38 (SLC38, SLC38A) transmembrane 10e protein

Properties

SIZE: MW = 56 kD entity length = 504 aa COMPARTMENT: cellular membrane MOTIF: Ser phosphorylation site {S52} Ser phosphorylation site {S54} N-glycosylation site {N74} transmembrane domain {83-103} transmembrane domain {106-126} transmembrane domain {144-164} transmembrane domain {187-207} transmembrane domain {213-233} N-glycosylation site {N247} N-glycosylation site {N248} N-glycosylation site {N252} N-glycosylation site {N323} transmembrane domain {324-344} transmembrane domain {366-386} transmembrane domain {408-428} transmembrane domain {431-451} transmembrane domain {471-491}

Database Correlations

OMIM 604437 UniProt Q99624 Pfam PF01490 Kegg hsa:1099

References

UniProt :accession Q99624