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solute carrier family 26 member 1 (SLC26A1, sulfate anion transporter 1, SAT-1)
Function:
- high affinity uptake of sulfate
- accepts oxalate, but not succinate as a cosubstrate
Structure:
- belongs to the SLC26A/sulP transporter (TC 2.A.53) family
- contains 1 STAS domain
Compartment: membrane
Expression:
- expressed in kidney & liver > pancreas, testis, brain, small intestine, colon, & lung
General
glycoprotein
solute carrier family 26 (SLC26, SLC26A)
transmembrane 8 protein
Properties
SIZE: MW = 75 kD
entity length = 701 aa
COMPARTMENT: cellular membrane
MOTIF: transmembrane domain {68-90}
transmembrane domain {94-116}
N-glycosylation site {N158}
N-glycosylation site {N163}
transmembrane domain {176-198}
transmembrane domain {255-277}
transmembrane domain {290-309}
transmembrane domain {342-364}
transmembrane domain {377-399}
transmembrane domain {412-434}
transmembrane domain {472-494}
STAS {527-687}
Database Correlations
OMIM 610130
UniProt Q9H2B4
PFAM correlations
Kegg hsa:1086
References
UniProt :accession Q9H2B4