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solute carrier family 22 member 20 (organic anion transporter 6, SLC22A20, OAT6)
Function:
- organic anion transporter that mediates the uptake of estrone sulfate
- inhibited by probenecid, propionate, 2-methylbutyrate, 3-methylbutyrate, benzoate, heptanoate & 2-ethylhaxanoate (putative)
Structure:
- belongs to the major facilitator superfamily, organic cation transporter family
Compartment: membrane (potential)
Alternative splicing: named isoforms=2
General
glycoprotein
membrane protein
solute carrier family 22 (SLC22, SLC22A)
transmembrane 11 protein
Properties
SIZE: entity length = 555 aa
MW = 60 kD
COMPARTMENT: cellular membrane
MOTIF: cytoplasmic domain {1-23}
transmembrane domain {24-44}
exoplasmic loop {45-137}
MOTIF: N-glycosylation site {N54}
N-glycosylation site {N114}
transmembrane domain {138-158}
cytoplasmic loop {159-166}
transmembrane domain {167-187}
exoplasmic loop {188-194}
transmembrane domain {195-215}
cytoplasmic loop {216-225}
transmembrane domain {226-246}
exoplasmic loop {247-250}
transmembrane domain {251-271}
cytoplasmic loop {272-339}
transmembrane domain {340-360}
exoplasmic loop {361-373}
transmembrane domain {374-394}
cytoplasmic loop {395-397}
transmembrane domain {398-418}
exoplasmic loop {419-429}
transmembrane domain {430-450}
cytoplasmic loop {451-485}
transmembrane domain {486-506}
exoplasmic domain {507-555}
Database Correlations
UniProt A6NK97
Pfam PF07690
References
UniProt :accession A6NK97