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solute carrier organic anion transporter family member 2B1; solute carrier family 21 member 9; organic anion transporter B; OATP-B; organic anion transporter polypeptide-related protein 2; OATP-RP2; OATPRP2 (SLCO2B1, KIAA0880, OATPB, SLC21A9)
Function:
- mediates the Na+ independent transport of organic anions such as taurocholate, the prostaglandins PGD2, PGE1, PGE2, leukotriene C4, thromboxane B2 & iloprost (putative)
Structure:
- belongs to the organo anion transporter (TC 2.A.60) family
Compartment: membrane
Alternative splicing: named isoforms=2
General
glycoprotein
phosphoprotein
solute carrier family 21 (SLC21, SLC21A)
transmembrane 10 protein
Properties
SIZE: entity length = 709 aa
MW = 77 kD
COMPARTMENT: cellular membrane
MOTIF: Ser phosphorylation site {S34}
transmembrane domain {118-138}
N-glycosylation site {N176}
transmembrane domain {186-206}
transmembrane domain {225-245}
transmembrane domain {277-297}
N-glycosylation site {N350}
transmembrane domain {371-391}
transmembrane domain {412-432}
transmembrane domain {443-463}
N-glycosylation site {N538}
transmembrane domain {557-577}
transmembrane domain {597-617}
transmembrane domain {651-671}
Database Correlations
OMIM 604988
UniProt O94956
Pfam PF03137
Kegg hsa:1130
References
UniProt :accession O94956