soluble guanyl cyclase (guanylate cyclase-1)

Function: - activated by nitric oxide in the presence of Mg⁺² or Mn+2 - half maximally inhibited at Ca⁺² of 120 nM Cofactor: binds 1 or 2 heme groups per heterodimer Subunits: - guanyl cyclase-alpha - guanyl cyclase-beta

General

Ca+2 binding protein guanyl cyclase or guanylate cyclase multisubunit protein

Properties

COMPARTMENT: cytoplasm MOTIF: heme-binding site COFACTOR-BOUND: heme{FE+2} FOR-BINDING-OF: O2 cGMP-binding site Ca+2-binding site SUBUNITS: guanyl cyclase-alpha subunit guanyl cyclase-beta subunit MISC-INFO: Ki [Ca+2] 120 NM

References

Vicent & Hope TINS 15:108 1992

Components

guanyl cyclase beta guanyl cyclase-alpha subunit guanyl cyclase beta