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small nuclear RNA-activating protein-43; SNAPc 43 kDa subunit; proximal sequence element-binding transcription factor gamma subunit; PSE-binding factor gamma subunit; PTF gamma subunit (SNAP43, SNAPC1)
Function:
- part of the SNAPc complex
- binds to proximal sequence element (PSE), a non-TATA-box basal promoter element
- recruits TBP & BRF2 to the U6 snRNA TATA box
Compartment: nucleus
General
nuclear protein
protein subunit
Properties
SIZE: MW = 43 kD
entity length = 368 aa
MOTIF: binding site
SITE: 1-168
FOR-BINDING-OF: small nuclear RNA-activating protein-50
binding site
SITE: 164-268
glutamate residue {347-352} (6)
Database Correlations
OMIM 600591
UniProt Q16533
Entrez Gene 6617
Kegg hsa:6617
References
- Henry RW, Sadowski CL, Kobayashi R, Hernandez N.
A TBP-TAF complex required for transcription of human snRNA
genes by RNA polymerase II and III.
Nature. 1995 Apr 13;374(6523):653-6.
PMID: 7715707
- UniProt :accession Q16533
Component-of
small nuclear RNA-activating protein complex (SNAPc)