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smudge cells
Etiology:
- chronic lymphocytic leukemia
Pathology:
- fragile leukocytes
Laboratory:
- peripheral smear
- disintegrated leukocyte with nuclear remnant enlarged & unconfined by nuclear membrane
General
abnormal morphologic structure (malformation)
References
Stedman's Medical Dictionary 27th ed, Williams &
Wilkins, Baltimore, 1999