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small proline-rich protein 4 (SPRR4)
Function:
- cross-linked envelope protein of keratinocytes
- role in UV-induced cornification
- cross-linked to membrane proteins by transglutaminase (probable)
Structure: belongs to the cornifin (SPRR) family
Compartment:
- cytoplasm, cell cortex -translocates to the cell periphery of keratinocytes & is integrated into both rigid & fragile cornified envelopes
Expression: induced by UV light
General
small proline-rich protein
Properties
SIZE: MW = 9 kD
entity length = 79 aa
COMPARTMENT: cytoplasm
MOTIF: glutamine-rich region {4-78}
MOTIF: glutamine residue (SEVERAL)
Database Correlations
UniProt Q96PI1
Pfam PF02389
References
UniProt :accession Q96PI1