small proline-rich protein 2G (SPR-2G, SPRR2G)

Function: - cross-linked envelope protein of keratinocytes - keratinocyte protein that first appears in the cell cytosol, ultimately becomes cross-linked to membrane proteins by transglutaminase. - process results in the formation of an insoluble envelope beneath the plasma membrane (putative) Structure: belongs to the cornifin (SPRR) family Compartment: cytoplasm (putative) Expression: - induced during squamous differentiation of epidermal keratinocytes (putative)

Properties

SIZE: MW = 8 kD entity length = 73 aa COMPARTMENT: cytoplasm MOTIF: proline-rich region SITE: 21-47 MOTIF: proline residue (SEVERAL) consensus repeat {21-29} consensus repeat {30-38} consensus repeat {39-47}

References

UniProt :accession Q9BYE4