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SLC6A13 (Na+/Cl- dependent GABA transporter 2 ) gene
A segmental duplication of chromosome 12 involving SLC6A13 is one of the few features distinguishing the human genome from the chimpanzee genome. [1,2]
Related
Na+/Cl- dependent GABA transporter 2; solute carrier family 6 member 13 (SLC6A13)
General
evolutionary divergent human gene
Properties
TEMPLATE-FOR: messenger RNA
TEMPLATE-FOR: Na+/Cl- dependent GABA transporter 2
LOCUS: human chromosome-12 P13.3
MOTIF: transcription factor binding site
transcriptional start site
exon
intron
transcriptional termination site
Database Correlations
Entrez Gene 6540
References
- Fortna A, Kim Y, MacLaren E, Marshall K, Hahn G, Meltesen L,
Brenton M, Hink R, Burgers S, Hernandez-Boussard T, Karimpour-
Fard A, Glueck D, McGavran L, Berry R, Pollack J, Sikela JM.
Lineage-specific gene duplication and loss in human and great
ape evolution.
PLoS Biol. 2004 Jul;2(7):E207. Epub 2004 Jul 13.
PMID: 15252450
- Goidts V, Szamalek JM, Hameister H, Kehrer-Sawatzki H.
Segmental duplication associated with the human-specific
inversion of chromosome 18: a further example of the impact of
segmental duplications on karyotype and genome evolution in
primates.
Hum Genet. 2004 Jul;115(2):116-22. Epub 2004 May 7.
PMID: 15133654