miR-126

Function: - silencing of miR-126 in breast cancer stem cells facilitates attachment of the malignant stem cells to endothelial cells, invasion of stromal tissue at sites of metastases, & angiogenesis to promote growth of the metastatic tumor - signals from endothelial cells seem important in silencing miR-126

Properties

FORM: miR-126

References

- Png KJ et al. A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells. Nature 2011 Dec 14; 481:190. PMID: 22170610