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sil proto-oncogene or SCL-interrupting locus gene
SCL-interrupting locus, fusion with SCL gene seen in 1;14 translocations of hematopoietic stem cell leukemias.
Related
hematopoietic stem cell leukemia [SCL] gene, tal1 or TCL5
SCL-interrupting locus protein
General
proto-oncogene
Properties
TEMPLATE-FOR: messenger RNA
TEMPLATE-FOR: SCL-interrupting locus protein
LOCUS: human chromosome-14
MOTIF: transcription factor binding site
transcriptional start site
exon
intron
transcriptional termination site
Database Correlations
OMIM 181590
MORBIDMAP 181590
References
- Aplan PD, Lombardi DP, Ginsberg AM, Cossman J, Bertness VL,
Kirsch IR.
Disruption of the human SCL locus by "illegitimate" V-(D)-J
recombinase activity.
Science. 1990 Dec 7;250(4986):1426-9.
PMID: 2255914