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sialyltransferase 8E; alpha-2,8-sialyltransferase 8F (ST8SIA6)
Function:
- prefers O-glycans to N-glycans or glycolipids as acceptor substrates
- the minimal acceptor substrate is the neuAc-alpha-2,3(6)-gal sequence at the non-reducing end of their carbohydrate groups (putative)
- protein modification; protein glycosylation
Structure: belongs to the glycosyltransferase 29 family
Compartment: Golgi membrane
General
glycoprotein
membrane protein
sialyltransferase
Properties
SIZE: entity length = 398 aa
MW = 45 kD
COMPARTMENT: golgi
MOTIF: transmembrane domain {4-24}
N-glycosylation site {N66}
N-glycosylation site {N93}
N-glycosylation site {N151}
cysteine residue {C186}
MODIFICATION: cysteine residue {C335}
N-glycosylation site {N196}
cysteine residue {C335}
MODIFICATION: cysteine residue {C186}
Database Correlations
UniProt P61647
Pfam PF00777
Kegg hsa:3385
References
- UniProt :accession P61647
- GGDB; Note: glycogene database
http://ggdb.muse.aist.go.jp/GGDB/index.jsp