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sialyltransferase 7E; alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase V; GD1 alpha synthase; galNAc alpha-2,6-sialyltransferase V (SIAT7E, ST6GALNAC5)
Function:
- role in the biosynthesis of ganglioside GD1a from GM1b
- exhibits higher activity with glycolipids than with glycoproteins (putative)
- protein modification; protein glycosylation
Structure: belongs to the glycosyltransferase 29 family
Compartment: Golgi membrane
General
glycoprotein
membrane protein
sialyltransferase
Properties
SIZE: entity length = 336 aa
MW = 38 kD
COMPARTMENT: golgi
MOTIF: transmembrane domain {9-29}
glutamine-rich region {38-49}
MOTIF: glutamine residue (SEVERAL)
cysteine residue {C96}
MODIFICATION: cysteine residue {C245}
N-glycosylation site {N137}
N-glycosylation site {N161}
cysteine residue {C245}
MODIFICATION: cysteine residue {C96}
Database Correlations
UniProt Q9BVH7
Pfam PF00777
Entrez Gene 81849
Kegg hsa:8184
References
- UniProt :accession Q9BVH7
- GGDB; Note: glycogene database
http://ggdb.muse.aist.go.jp/GGDB/index.jsp