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SH3 & multiple anykrin repeat domains (Shank) protein


Interactions

molecular events

Specific

SH3 & multiple ankyrin repeat domains protein 1; Shank1; somatostatin receptor-interacting protein; SSTR-interacting protein; SSTRIP (SHANK1) SH3 & multiple ankyrin repeat domains protein 2; Shank2; cortactin-binding protein 1; cortBP1; proline-rich synapse-associated protein 1 (SHANK2, CORTBP1, KIAA1022, PROSAP1) SH3 & multiple ankyrin repeat domains protein 3; Shank3; proline-rich synapse-associated protein 2; ProSAP2 (SHANK3 KIAA1650 PSAP2)

General

scaffold protein

Properties

COMPARTMENT: postsynaptic density CELL-REGION: dendritic spine CELL: neuron MOTIF: ankyrin repeat NAME: ankyrin repeat membrane region src homology 3 [SH3] domain sterile alpha motif NAME: sterile alpha motif SITE: C-TERMINAL

References

  1. Sheng M. Molecular organization of the postsynaptic specialization. Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7058-61. Review. PMID: 11416187

Component-of

molecular complex