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sex reversal disorder

Genetics: - chromosomal translocation t(X;Y)(p22;p11) involving PRKX with PRKY is a cause of sex reversal disorder - chromosomal translocations proximal to PRKY account for ~30% of cases of sex reversal disorder in XX males & XY females

General

genetic disease of the endocrine system

References

UniProt :accession P51817