SET & MYND domain-containing protein 1 (SMYD1)

Function: - transcriptional repressor - essential for cardiomyocyte differentiation & cardiac morphogenesis - interacts with HDAC1, HDAC2 & HDAC3 Structure: - contains 1 MYND-type zinc finger - contains 1 SET domain Compartment: cytoplasm, nucleus

General

SET & MYND domain-containing protein (SMYD) transcriptional silencer (transcriptional repressor)

Properties

SIZE: MW = 57 kD entity length = 490 aa COMPARTMENT: cytoplasm cell nucleus MOTIF: Zinc finger NAME: Zinc finger SITE: 52-90 EFFECTOR-BOUND: Zn+2 SET domain {126-259}

Database Correlations

OMIM 606846 UniProt Q8NB12 PFAM correlations

References

UniProt :accession Q8NB12