serotonin [5HT]-5A receptor; 5-hydroxytryptamine receptor 5A; 5-HT-5A; 5-HT-5; serotonin receptor 5A (HTR5A)

Function: - one of several receptors for 5-hydroxytryptamine (serotonin) - activityis mediated by G proteins Structure: belongs to the G-protein coupled receptor 1 family Compartment: cell membrane

General

glycoprotein serotonin [5HT]-5 receptor

Properties

SIZE: entity length = 357 aa MW = 40 kD COMPARTMENT: synaptic membrane CELL: neuron MOTIF: exoplasmic domain {1-40} MOTIF: N-glycosylation site {N6} N-glycosylation site {N21} transmembrane domain {41-63} cytoplasmic loop {64-78} transmembrane domain {79-99} exoplasmic loop {100-115} transmembrane domain {116-137} MOTIF: cysteine residue {C120} MODIFICATION: cysteine residue {C192} cytoplasmic loop {138-158} transmembrane domain {159-181} exoplasmic loop {182-198} MOTIF: cysteine residue {C192} MODIFICATION: cysteine residue {C120} transmembrane domain {199-219} cytoplasmic loop {220-282} transmembrane domain {283-303} exoplasmic loop {304-320} transmembrane domain {321-341} cytoplasmic domain {342-357}

Database Correlations

OMIM 601305 UniProt P47898 Pfam PF00001 Entrez Gene 3361 Kegg hsa:3361

References

UniProt :accession P47898