serine carboxypeptidase CPVL (carboxypeptidase, vitellogenic-like; vitellogenic carboxypeptidase- like protein; VCP-like proteinl; HVLP; CPVL; VL;P PSEC0124; UNQ197/PRO223)

Function: - role in digestion of phagocytosedparticles in lysosomes, participation in an inflammatory protease cascade, & trimming of peptides for antigen presentation (putative) Structure: - belongs to the peptidase S10 family Expression: - expressed in macrophages, but not in other leukocytes? - expressed in heart, kidney > spleen, leukocytes, placenta

General

carboxypeptidase glycoprotein

Properties

SIZE: MW = 54 kD entity length = 476 aa MOTIF: signal sequence {1-22} N-glycosylation site {N81} N-glycosylation site {N132} serine residue {S204} N-glycosylation site {N307} N-glycosylation site {N346} aspartate residue {D388} histidine residue {H448}

Database Correlations

UniProt Q9H3G5 Pfam PF00450

References

UniProt :accession Q9H3G5