semaphorin-4G (SEMA4G, KIAA1619)

Function: - may play a role in axon guidance (putative) Structure: - belongs to the semaphorin family - contains 1 Ig-like C2-type domain (immunoglobulin-like) - contains 1 PSI domain - contains 1 sema domain Compartment: - membrane; single-pass type 1 membrane protein Alternative splicing: - named isoforms=2

General

glycoprotein phosphoprotein secreted protein semaphorin or semaphorin/collapsin family protein

Properties

SIZE: entity length = 838 aa MW = 91 kD COMPARTMENT: cellular membrane MOTIF: signal sequence {1-17} Sema {35-505} MOTIF: N-glycosylation site {N55} cysteine residue {C104} MODIFICATION: cysteine residue {C115} N-glycosylation site {N111} cysteine residue {C115} MODIFICATION: cysteine residue {C104} N-glycosylation site {N126} cysteine residue {C133} MODIFICATION: cysteine residue {C142} cysteine residue {C142} MODIFICATION: cysteine residue {C133} cysteine residue {C270} MODIFICATION: cysteine residue {C377} cysteine residue {C294} MODIFICATION: cysteine residue {C337} cysteine residue {C337} MODIFICATION: cysteine residue {C294} cysteine residue {C377} MODIFICATION: cysteine residue {C270} N-glycosylation site {N388} PSI {507-558} MOTIF: N-glycosylation site {N542} proline-rich region SITE: 565-568 MOTIF: proline residue (SEVERAL) immunoglobulin superfamily domain {567-649} MOTIF: cysteine residue {C584} MODIFICATION: cysteine residue {C632} N-glycosylation site {N598} cysteine residue {C632} MODIFICATION: cysteine residue {C584} transmembrane domain {676-696} proline-rich region SITE: 763-774 MOTIF: proline residue (SEVERAL) Ser phosphorylation site {S795}

Database Correlations

UniProt Q9NTN9 PFAM correlations Entrez Gene 57715 Kegg hsa:57715