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serpin enzyme complex [sec] receptor


Interactions

molecular events

General

cell surface receptor

Properties

COMPARTMENT: plasma membrane MOTIF: ligand-binding site transmembrane domain

References

  1. Joslin G, Fallon RJ, Bullock J, Adams SP, Perlmutter DH. The SEC receptor recognizes a pentapeptide neodomain of alpha 1-antitrypsin-protease complexes. J Biol Chem. 1991 Jun 15;266(17):11282-8. PMID: 1645729
  2. Perlmutter DH, Joslin G, Nelson P, Schasteen C, Adams SP, Fallon RJ. Endocytosis and degradation of alpha 1-antitrypsin-protease complexes is mediated by the serpin-enzyme complex (SEC) receptor. J Biol Chem. 1990 Oct 5;265(28):16713-6. PMID: 2211587 - Perlmutter DH, Glover GI, Rivetna M, Schasteen CS, Fallon RJ. Identification of a serpin-enzyme complex receptor on human hepatoma cells and human monocytes. Proc Natl Acad Sci U S A. 1990 May;87(10):3753-7. PMID: 2160076