Search
mammaglobin-B; lacryglobin; lipophilin-C; mammaglobin-2; secretoglobin family 2A member 1 (SCGB2A1, LIPHC, MGB2, UGB3)
Function:
1) may bind androgens & other steroids
2) may also bind estramustine, a chemotherapeutic agent used for prostate cancer
3) may be under transcriptional regulation of steroid hormones
4) heterodimer of a lipophilin A & a lipophilin C (mammaglobin B)
Structure:
- belongs to the secretoglobin family, lipophilin subfamily
Expression:
- expressed in steroid responsive tissues (prostate, testis, uterus, breast & ovary)
- expressed in thymus, trachea, kidney, & salivary gland
General
secretoglobin
Properties
SIZE: entity length = 95 aa
MW = 11 kD
COMPARTMENT: extracellular compartment
MOTIF: signal sequence {1-18}
N-glycosylation site {N68}
Database Correlations
OMIM 604398
UniProt O75556
Pfam PF01099
Entrez Gene 4246
Kegg hsa:4246
References
- UniProt :accession O75556
- http://www.gene.ucl.ac.uk/nomenclature/genefamily/scgb.html