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secretin receptor; SCT-R (SCTR)

Function: - receptor for secretin - activity of is mediated by G proteins which activate adenylyl cyclase (Gs proteins) Structure: belongs to the G-protein coupled receptor 2 family Compartment: cell membrane

General

glycoprotein G-protein coupled receptor; serpentine receptor

Properties

SIZE: entity length = 440 aa MW = 50 kD COMPARTMENT: cellular membrane MOTIF: signal sequence {1-22} exoplasmic domain {23-143} MOTIF: N-glycosylation site {N72} N-glycosylation site {N100} N-glycosylation site {N106} N-glycosylation site {N128} transmembrane domain {144-167} cytoplasmic loop {168-174} transmembrane domain {175-194} exoplasmic loop {195-216} transmembrane domain {217-240} cytoplasmic loop {241-254} transmembrane domain {255-276} exoplasmic loop {277-294} MOTIF: N-glycosylation site {N291} transmembrane domain {295-317} cytoplasmic loop {318-343} transmembrane domain {344-362} exoplasmic loop {363-369} transmembrane domain {370-392} cytoplasmic domain {393-440}

Database Correlations

OMIM 182098 UniProt P47872 PFAM correlations Kegg hsa:6344

References

UniProt :accession P47872