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screening for hyperhomocysteinemia
Indications:
1) atherosclerosis without conventional risk factors
2) premature atherosclerosis (before age 60)
3) high risk for premature atherosclerosis
a) 1st degree relative with premature atherosclerosis
b) tobaccoism
c) hypertension
4) chronic renal failure
5) unexplained deep vein thrombosis (DVT)
6) systemic lupus erythematosus
7) severe psoriasis
8) recipients of solid organ transplant
9) pharmacologic agents elevating plasma homocysteine levels
* screening should be deferred until 8 weeks after recovery from serious systemic illness
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hyperhomocysteinemia
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screening