scavenger receptor cysteine-rich domain-containing group B protein (S4-SRCRB, SRCRB4D)

Structure: contains 4 SRCR domains Compartment: secreted (putative) Alternative splicing: named isoforms=3 Expression: - not induced by a combination of interleukin-1 alpha, interleukin-6 & dexamethasone

Properties

SIZE: entity length = 575 aa MW = 61 kD COMPARTMENT: extracellular compartment MOTIF: signal sequence {1-47} SRCR 1 {58-158} MOTIF: cysteine residue {C83} MODIFICATION: cysteine residue {C147} cysteine residue {C96} MODIFICATION: cysteine residue {C157} cysteine residue {C127} MODIFICATION: cysteine residue {C137} cysteine residue {C137} MODIFICATION: cysteine residue {C127} cysteine residue {C147} MODIFICATION: cysteine residue {C83} cysteine residue {C157} MODIFICATION: cysteine residue {C96} SRCR 2 {189-289} MOTIF: cysteine residue {C214} MODIFICATION: cysteine residue {C278} cysteine residue {C227} MODIFICATION: cysteine residue {C288} cysteine residue {C258} MODIFICATION: cysteine residue {C268} cysteine residue {C268} MODIFICATION: cysteine residue {C258} cysteine residue {C278} MODIFICATION: cysteine residue {C214} cysteine residue {C288} MODIFICATION: cysteine residue {C227} SRCR 3 {344-444} MOTIF: cysteine residue {C369} MODIFICATION: cysteine residue {C433} cysteine residue {C382} MODIFICATION: cysteine residue {C443} cysteine residue {C413} MODIFICATION: cysteine residue {C423} cysteine residue {C423} MODIFICATION: cysteine residue {C413} cysteine residue {C433} MODIFICATION: cysteine residue {C369} cysteine residue {C443} MODIFICATION: cysteine residue {C382} SRCR 4 {473-573} MOTIF: cysteine residue {C498} MODIFICATION: cysteine residue {C562} cysteine residue {C511} MODIFICATION: cysteine residue {C572} cysteine residue {C542} MODIFICATION: cysteine residue {C552} cysteine residue {C552} MODIFICATION: cysteine residue {C542} cysteine residue {C562} MODIFICATION: cysteine residue {C498} cysteine residue {C572} MODIFICATION: cysteine residue {C511}

Database Correlations

OMIM 607639 UniProt Q8WTU2 Pfam PF00530 Kegg hsa:1368

References

UniProt :accession Q8WTU2