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scavenger receptor class B member 2 (CD36L2, lysosome membrane protein 2, LIMP2, 85 kDa lysosomal membrane sialoglycoprotein, LGP85)
Function: may act as a lysosomal receptor
Structure:
- belongs to the CD36 family
- mass=54158.97
Compartment:
- lysosome membrane
Pathology:
- defects in SCARB2 are the cause of action myoclonus-renal failure syndrome
Related
CD36; platelet glycoprotein 4; platelet glycoprotein IV; GPIV; glycoprotein IIIb; GPIIIB; leukocyte differentiation antigen CD36; PAS IV; PAS-4; platelet collagen receptor; fatty acid translocase; FAT; Thrombospondin receptor (GP3B, GP4)
General
glycoprotein
scavenger receptor
Properties
SIZE: MW = 54 kD
entity length = 477 aa
COMPARTMENT: lysosome
cellular membrane
MOTIF: cytoplasmic domain {1-3}
transmembrane domain {4-26}
exoplasmic loop {27-432}
MOTIF: N-glycosylation site {N44}
N-glycosylation site {N67}
N-glycosylation site {N104}
N-glycosylation site {N205}
N-glycosylation site {N223}
N-glycosylation site {N248}
N-glycosylation site {N303}
N-glycosylation site {N324}
N-glycosylation site {N411}
N-glycosylation site {N429}
transmembrane domain {433-458}
cytoplasmic domain {459-477}
Database Correlations
OMIM correlations
MORBIDMAP 602257
UniProt Q14108
Pfam PF01130
Kegg hsa:950
References
UniProt :accession Q14108