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sal-like protein 3; zinc finger protein 796; zinc finger protein SALL3; hSALL3 (SALL3, ZNF796)
Function:
- probable transcription factor
Structure:
- belongs to the sal C2H2-type Zn+2-finger protein family
- contains 9 C2H2-type Zn+2 fingers
Compartment: nucleus (probable)
Alternative splicing: named isoforms=4
Expression:
- widely expressed in adult with highest levels in heart
- expressed in fetal brain (in neurons of hippocampus, cortex, mediodorsal & ventrolateral thalamic nuclei, putamen, cerebellum & brainstem)
- in fetal brain of the 24th gestational week
General
C2H2 type zinc finger protein
nuclear protein
Properties
SIZE: entity length = 1300 aa
MW = 135 kD
COMPARTMENT: cell nucleus
MOTIF: alanine-rich region {198-201}
MOTIF: alanine residue (SEVERAL)
glutamine-rich region {213-216}
MOTIF: glutamine residue (SEVERAL)
Zn finger C2H2-type
SITE: 420-442
EFFECTOR-BOUND: Zn+2
Zn finger C2H2-type
SITE: 448-470
EFFECTOR-BOUND: Zn+2
Zn finger C2H2-type
SITE: 679-701
EFFECTOR-BOUND: Zn+2
Zn finger C2H2-type
SITE: 707-729
EFFECTOR-BOUND: Zn+2
Zn finger C2H2-type
SITE: 739-761
EFFECTOR-BOUND: Zn+2
serine-rich region {897-902}
MOTIF: serine residue (SEVERAL)
Zn finger C2H2-type
SITE: 977-999
EFFECTOR-BOUND: Zn+2
Zn finger C2H2-type
SITE: 1005-1027
EFFECTOR-BOUND: Zn+2
Zn finger C2H2-type
SITE: 1113-1135
EFFECTOR-BOUND: Zn+2
Zn finger C2H2-type
SITE: 1141-1163
EFFECTOR-BOUND: Zn+2
Database Correlations
OMIM 605079
UniProt Q9BXA9
Pfam PF00096
Entrez Gene 27164
Kegg hsa:27164
References
UniProt :accession Q9BXA9