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salusin-alpha
Function:
- salusin-alpha & salusin-beta are produced by proteolytic processing of prosalusin
- salusin-alpha & salusin-beta may be endocrine &/or paracrine factors able to increase intracellular Ca+2 & induce cell mitogenesis
- salusins may also be potent hypotensive peptides
- amidation of salusin-alpha(29-Gly) by peptidylglycine alpha- amidating monooxygenase, PAM, converts Lys-241-Gly-242 to Lys-241-NH2 & gives raise to salusin-alpha
- salusin-alpha & salusin-beta are only produced from an alternatively spliced mRNA of TOR2A, isoform 4
Related
prosalusin (torsin-2A, torsin family 2 member A, [Contains: Salusin-alpha; Salusin-beta], TOR2A)
General
secreted protein
Properties
COMPARTMENT: extracellular compartment
References
UniProt :accession Q8N2E6