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Rossmann fold

One of the 5 of the most populated protein folds: - immunoglobulin fold - oligonucleotide-binding fold - Rossman fold - alpha/beta plait - TIM barrels It occurs as an ATP-binding domain in the N-terminal region of amino-acyl tRNA synthetases.

General

peptide motif

References

  1. Mirny LA, Shakhnovich EI. Universally conserved positions in protein folds: reading evolutionary signals about stability, folding kinetics and function. J Mol Biol. 1999 Aug 6;291(1):177-96. PMID: 10438614
  2. Eriani G, Delarue M, Poch O, Gangloff J, Moras D. Partition of tRNA synthetases into two classes based on mutually exclusive sets of sequence motifs. Nature. 1990 Sep 13;347(6289):203-6. PMID: 220397
  3. prosite :accession PS00178