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RNA polymerase II subunit A C-terminal domain phosphatase SSU72 like protein 5; RNA polymerase II subunit A C-terminal domain phosphatase SSU72L5; CTD phosphatase SSU72L5 (SSU72L5)
Function:
- protein phosphatase
- catalyzes dephosphorylation of the C-terminal domain of RNA polymerase II
- plays a role in RNA processing & termination
H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] + phosphate
H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate
Structure: belongs to the SSU72 phosphatase family,
Compartment: nucleus
General
nuclear protein
phosphoprotein phosphatase
Properties
SIZE: entity length = 194 aa
MW = 22 kD
COMPARTMENT: cell nucleus
MOTIF: active site
STATE: active state
Database Correlations
UniProt A0A1W2PQ64
Pfam PF04722
ENZYME 3.1.3.16
References
UniProt :accession A0A1W2PQ64