RNA polymerase II-associated factor 1 homolog (hPAF1, pancreatic differentiation protein 2, PAF1, PD2)

Function: - component of the mammalian PAF1 complex Structure: belongs to the PAF1 family Compartment: - nucleus - punctuate distribution throughout the nucleus except in nucleoli & the perinuclear chromatin Alternative splicing: named isoforms=2

General

nuclear protein phosphoprotein protein subunit

Properties

SIZE: entity length = 531 aa MW = 60 kD COMPARTMENT: cell nucleus MOTIF: coiled coil {352-400} glutamate-rich region {358-452} MOTIF: glutamate residue (SEVERAL) Ser phosphorylation site {S456} Ser phosphorylation site {S460} Ser phosphorylation site {S466}

Database Correlations

UniProt Q8N7H5 Pfam PF03985

References

UniProt :accession Q8N7H5