RNA polymerase-associated protein RTF1 homolog (RTF1, KIAA0252)

Function: - role in transcription-coupled histone modification - role in regulation of transcription - required for maximal induction of heat-shock genes - interacts with the RNA polymerase 2 complex - may interact with the PAF1 complex Structure: contains 1 Plus-3 domain Compartment: nucleus, nucleoplasm (putative)

General

nuclear protein phosphoprotein

Properties

SIZE: MW = 77 kD entity length = 670 aa COMPARTMENT: cell nucleus MOTIF: serine-rich region {95-133} MOTIF: serine residue (SEVERAL) glutamate-rich region {134-305} MOTIF: glutamate residue (SEVERAL) lysine-rich region {174-267} MOTIF: lysine residue (SEVERAL) Plus-3 {317-422} coiled coil {486-520} Ser phosphorylation site {S657}

Database Correlations

UniProt Q92541 Pfam PF03126

References

UniProt :accession Q92541