RNA polymerase-associated protein LEO1 (replicative senescence down-regulated leo1-like protein, LEO1, RDL)

Function: 1) component of the PAF1 complex 2) interacts with CDC73 Alternative splicing: named isoforms=2 Expression: - expressed in skeletal muscle, heart > placenta, liver

General

nuclear protein phosphoprotein

Properties

SIZE: MW = 75 kD entity length = 666 aa COMPARTMENT: cell nucleus MOTIF: Ser phosphorylation site {S151} Ser phosphorylation site {S154} Ser phosphorylation site {S162} Ser phosphorylation site {S171} Ser phosphorylation site {S179} Ser phosphorylation site {S279} Ser phosphorylation site {S630} Ser phosphorylation site {S658}

Database Correlations

UniProt Q8WVC0 Pfam PF04004

References

UniProt :accession Q8WVC0