RNA polymerases 1, 2, & 3 subunit RPABC1 (RNA polymerases 1, 2, & 3 subunit ABC1, RNA polymerase 2 23 kD subunit, RNA polymerase 2 subunit E, RNA polymerase 2 subunit 5, POLR2E, RPABC1, RPB25, RBP5, XAP4)

Function: - common component of RNA polymerases 1, 2 & 3 - in RNA polymerase 2, POLR2E is part of the lower jaw surrounding the central large cleft & thought to grab the incoming DNA template, seems to be the major component in this process (putative) - subunit is present in 2-fold molar excess over other subunits - interacts with RMP - interacts with HBV protein Structure: - N-terminus is blocked - belongs to the archaeal rpoH/eukaryotic RPB5 RNA polymerase subunit family Compartment: nucleus (putative)

General

nuclear protein rna polymerase subunit

Properties

SIZE: MW = 25 kD entity length = 210 aa COMPARTMENT: cell nucleus

Database Correlations

OMIM 180664 UniProt P19388 PFAM correlations Kegg hsa:5434

References

UniProt :accession P19388